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    1.     David S.Baldwin, Christer Allgulander, Alfredo Carlo Altamura, Jules Angst, Borwin Bandelow, Johan den Boer, Patrice Boyer, Simon Davies, Bernardo dell’Osso, Elias Eriksson, Naomi Fineberg, Mats Fredrikson, Andres Herran, Eduard Maron, Andres Metspalu, David Nutt, Nic van der Wee, Jose Luis Vasquez-Barquero, Joseph Zohar. (2010) Manifesto for a European Anxiety Disorders Research Network. European Neuropsychopharmacology (2010 ) 20, 426-432

     

    2.     Nikopensius T, Birnbaum S, Ludwig KU, Jagomägi T, Saag M, Herms S, Knapp M, Hoffmann P, Nöthen MM, Metspalu A, Mangold E. Susceptibility locus for nonsyndromic cleft lip with or without cleft palate on chromosome 10q25 confers risk in Estonian patients. Eur J Oral Sci 2010; 118: 317-319.

     

    3.     Jagomägi T, Nikopensius T, Krjutškov K, Tammekivi V, Viltrop T, Saag M, Metspalu A. MTHFR and MSX1 contribute to the risk of nonsyndromic cleft lip/palate. Eur J Oral Sci 2010; 118: 213-220.

     

    4.     Allebrandt, K.V.; Teder-Laving, M.; Akyol, M.; Pichler, I.; Müller-Myhsok, B.; Pramstaller, P.; Merrow, M.; Meitinger, T.; Metspalu, A.; Roenneberg, T., CLOCK Gene Variants Associate with Sleep Duration in Two Independent Populations. Biological Psychiatry 2010;  67

     

    5.     Thorgeirsson, TE.; Gudbjartsson, DF.; Surakka, I.; Vink, JM.; Amin, N.; Geller, F.; Sulem, P.; Rafnar, T.; Esko, T.; Walter, S.; Gieger, C.; Rawal, R.; Mangino, M.; Prokopenko, I.; Mägi, R.; Keskitalo, K.; Gudjonsdottir, IH.; Gretarsdottir, S.; Stefansson, H.; Thompson, JR.; Aulchenko, YS.; Nelis, M.; Aben, KK.; den, Heijer, M.; Dirksen, A.; Ashraf, H.; Soranzo, N.; Valdes, AM.; Steves, C.; Uitterlinden, AG.; Hofman, A.; Tönjes, A.; Kovacs, P.; Hottenga, JJ.; Willemsen, G.; Vogelzangs, N.; Döring, A.; Dahmen, N.; Nitz, B.; Pergadia, ML.; Saez, B.; De, Diego, V.; Lezcano, V.; Garcia-Prats, MD.; Ripatti, S.; Perola, M.; Kettunen, J.; Hartikainen, AL.; Pouta, A.; Laitinen, J.; Isohanni, M.; Huei-Yi, S.; Allen, M.; Krestyaninova, M.; Hall, AS.; Jones, GT.; van, Rij, AM.; Mueller, T.; Dieplinger, B.; Haltmayer, M.; Jonsson, S.; Matthiasson, SE.; Oskarsson, H.; Tyrfingsson, T.; Kiemeney, LA.; Mayordomo, JI.; Lindholt, JS.; Pedersen, JH.; Franklin, WA.; Wolf, H.; Montgomery, GW.; Heath, AC.; Martin, NG.; Madden, PA.; Giegling, I.; Rujescu, D.; Järvelin, MR.; Salomaa, V.; Stumvoll, M.; Spector, TD.; Wichmann, HE.; Metspalu, A.; Samani, NJ.; Penninx, BW.; Oostra, BA.; Boomsma, DI.; Tiemeier, H.; van, Duijn, CM.; Kaprio, J.; Gulcher, JR.; McCarthy, MI.; Peltonen, L.; Thorsteinsdottir, U.; Stefansson, K (2010) . Sequence variants at CHRNB-CHRNA6 and affect smoking behavior. Nature Genetics 42 (5), 448-453

     

    6.     Tamboom, K.; Kaasik, K.; Arsavskaja, J.; Tekkel, M., Lilleorg, A.; Padrik, P.; Metspalu, A.; Veidebaum, T. (2010) BRCA1 mutations in women with familial or early-onset breast cancer and BRCA2 mutations in familial cancer in Estonia. Hereditary Cancer in Clinical Practice, 8,4

    BMC Neurology (1) 10, 17

     

    7.     Braschinsky, M.; Tamm, R.; Beetz, C.; Sachez-Ferrero, E.; Raukas, E.; Lüüs, SM.; Gross-Paju, K.; Boillot, C.; Canzian, F.; Metspalu, A.; Haldre, S. (2010) Unique spectrum of SPAST variants in Estonian HSP patients: presence of benign missense changes but lack of exonic rearrangements. Eesti Arst, 89 (3), 165-170

     

    8.     Ellinor, Patrick; Lunetta, Kathryn; Glazer, Nicole; Pfeufer, Arne; Alonso, Alvaro; Chung, Mina; Sinner, Moritz F; de Bakker, Paul I. W; Mueller, Martina; Lubitz, Steven A; Fox, Ervin; Darbar, Dawood; Smith, Nicholas L; Smith, Jonathan D; Schnabel, Renate B; Soliman, Elsayed Z; Rice, Kenneth M; Van Wagoner, David R; Beckmann, Britt-M; van Noord, Charlotte; Wang, Ke; Ehret, Georg B; Rotter, Jerome I; Hazen, Stanley L; Steinbeck, Gerhard; Smith, Albert V; Launer, Lenore J; Harris, Tamara B; Makino, Seiko; Nelis, Mari; Milan, David J; Perz, Siegfried; Esko, Tõnu; Köttgen, Anna; Moebus, Susanne; Newton-Cheh, Christopher; Li, Man; Möhlenkamp, Stefan; Wang, Thomas J; Kao, W. H. Linda; Vasan, Ramachandran S; Nöthen, Markus M; MacRae, Calum A; Ch Stricker, Bruno H; Hofman, Albert; Uitterlinden, André G; Levy, Daniel; Boerwinkle, Eric; Metspalu, Andres; Topol, Eric J; Chakravarti, Aravinda; Gudnason, Vilmundur; Psaty, Bruce M; Roden, Dan M; Meitinger, Thomas; Wichmann, H-Erich; Witteman, Jacqueline C. M; Barnard, John; Arking, Dan E; Benjamin, Emelia J; Heckbert, Susan R; Kääb, Stefan (2010). Common variants in KCNN3 are associated with lone atrial fibrillation. Nature Genetics , 42 (3), 240-244

     

    9.     Braschinsky, M.; Tamm, R.; Beetz, C.; Sachez-Ferrero, E.; Raukas, E.; Lüüs, SM.; Gross-Paju, K.; Boillot, C.; Canzian, F.; Metspalu, A.; Haldre, S. (2010). Unique spectrum of SPAST variants in Estonian HSP patients: presence of benign missense changes but lack of exonic rearrangements. BMC Neurology, 10 (1) 17

     

    10.   Theodoraki, E.V.; Nikopensius, T.; Suhorutsenko, J.; Peppes, V.; Fili, P.; Kolovou, G.; Papamikos, V.; Richter, D.; Zakopoulos, N.; Krjutskov, K.; Metspalu, A.; Dedoussis, G.V. (2010) Fibrinogen beta variants confer protection against coronary artery disease in a Greek case-control study.  BMC Medical Genetics, 11 (28), e28.

     

    11.   Walters, S. Jacquemont, A. Valsesia, A. J. de Smith, D. Martinet, J. Andersson, M. Falchi, F. Chen, J. Andrieux, S. Lobbens, B. Delobel, F. Stutzmann, J. S. El-Sayed Moustafa, J.-C. Chèvre, C. Lecoeur, V. Vatin, S. Bouquillon, J. L. Buxton, O. Boute, M. Holder-Espinasse, J.-M. Cuisset, M.-P. Lemaitre, A.-E. Ambresin, A. Brioschi, M. Gaillard, V. Giusti, F. Fellmann, A. Ferrarini, N. Hadjikhani, D. Campion, A. Guilmatre, A. Goldenberg, N. Calmels, J.-L. Mandel, C. Le Caignec, A. David, B. Isidor, M.-P. Cordier, S. Dupuis-Girod, A. Labalme, D. Sanlaville, M. Béri-Dexheimer, P. Jonveaux, B. Leheup, K. Õunap, E. G. Bochukova, E. Henning, J. Keogh, R. J. Ellis, K. D. MacDermot, M. M. van Haelst, C. Vincent-Delorme, G. Plessis, R. Touraine, A. Philippe, V. Malan, M. Mathieu-Dramard, J. Chiesa, B. Blaumeiser, R. F. Kooy, R. Caiazzo, M. Pigeyre, B. Balkau, R. Sladek, S. Bergmann, V. Mooser, D. Waterworth, A. Reymond, P. Vollenweider, G. Waeber, A. Kurg, P. Palta, T. Esko, A. Metspalu, M. Nelis, P. Elliott, A.-L. Hartikainen, M. I. McCarthy, L. Peltonen, L. Carlsson, P. Jacobson, L. Sjöström, N. Huang, M. E. Hurles, S. O’Rahilly, I. S. Farooqi, K. Männik, M.-R. Jarvelin, F. Pattou, D. Meyre, A. J. Walley, L. J. M. Coin, A. I. F. Blakemore, P. Froguel & J. S. Beckmann (2010) A new highly penetrant form of obesity due to deletions on chromosome 16p11.2 R. G. Nature 463, 671-675 (4 February 2010)

     

    12.   Viltrop, T.; Krjutškov, K.; Palta, P.; Metspalu, A (2010) . Comparison of DNA extraction methods for multiplex PCR. Analytical Biochemistry, 398 (2) , 260-262

     

    13.   Vooder, T., Välk, K., Palta ,P., Kolde, R., Metspalu, A. (2009). Parallel comparison of NSCLC CNV, survival and gene expression profiles in Estonian population. Journal of Thoracic Oncology: 13 th World Conference on Lung Cancer; San Francisco, USA; 31.07-04.08.2009. Supplement: Suppl. 1, 932

     

    14.   Nikopensius T, Ambrozaityté L, Ludwig KU, Birnbaum S, Jagomägi T, Saag M, Matulevičiené A, Linkevičiené L, Herms S, Knapp M, Hoffmann P, Nöthen MM, Kučinskas V, Metspalu A, Mangold E. (2009). Replication of novel susceptibility locus for nonsyndromic cleft lip with or without cleft palate on chromosome 8q24 in Estonian and Lithuanian patients. Am J Med Genet Part A 149A:2551–2553.

     

    15.   Theodoraki, E.V; Nikopensius, T.; Suhorutšenko, J.; Papamikos, V.; Kolovou, G.D.; Peppes, V.; Panagiotakos, D.; Limberi, S.; Zakopoulos, N.; Metspalu, A.; Dedoussis, G.V. ROS1 Asp2213Asn polymorphism is not associated with coronary artery disease in a Greek case-control study. Clinical Chemistry and Laboratory Medicine. 2009, 1471-1473

     

    16.   Tõnisson, Neeme; Oitmaa, Eneli; Krjutskov, Kaarel; Pullat, Janne; Lind, Ilona; Leego, Merike; Kurg, Ants; Metspalu, Andres (2009). Arrayed primer extension microarrays for molecular diagnostics. MOLECULAR DIAGNOSTICS 2nd edition 2009

     

     

    17.   Maron E, Tammiste A, Kallassalu K, Eller T, Vasar V, Nutt DJ, Metspalu A  Serotonin transporter promoter region polymorphisms do not influence treatment response to escitalopram in patients with major depression. 2009 Jun;19(6):451-6. Epub 2009 Mar 9

     

    18.   Mari Nelis, Tõnu Esko, Reedik Mägi, Fritz Zimprich, Alexander Zimprich, Draga Toncheva, Sena Karachanak, Milan Macek, Tereza Piskáčková, Ivan Balaščák, Leena Peltonen, Eveliina Jakkula, Karola Rehnström, Mark Lathrop, Simon Heath, Pilar Galan, Michael Krawczak, Stefan Schreiber, Thomas Meitinger,Arne Pfeufer, H-Erich Wichmann, Béla Melegh, Noémi Polgár, Daniela Toniolo, Paolo Gasparini, Pio D'Adamo, Janis Klovins, Liene Nikitina-Zake, Vaidutis Kučinskas, Jūratė Kasnauskienė, Jan Lubinski, Tadeusz Debniak, Svetlana Limborska, Andrey Khrunin, Xavier Estivill, Raquel Rabionet, Sara Marsal, Antonio Julia, Stylianos E. Antonarakis, Samuel Deutsch, Christelle Borel, Homa Attar-Cohen, Marilyne Gagnebin, Maido Remm and Andres Metspalu, Genetic Structure of Europeans: a view from the North-East PlosOne 2009,

     

    19.   Lagiou P, Georgila C, Minaki P, Ahrens W, Pohlabeln H, Benhamou S, Bouchardy C, Slamova A, Schejbalova M, Merletti F, Richiardi L, Kjaerheim K, Agudo A, Castellsague X, Macfarlane TV, Macfarlane GJ, Talamini R, Barzan L, Canova C, Simonato L, Lowry R, Conway DI, McKinney PA, Znaor A, McCartan BE, Healy C, Nelis M, Metspalu A, Marron M, Hashibe M, Brennan PJ,  Alcohol-related cancers and genetic susceptibility in Europe: the ARCAGE project: study samples and data collection. Eur. J Cancer Prev. 2009, 18, 76-84

     

    20.   Canova C, Hashibe M, Simonato L, Nelis M, Metspalu A, Lagiou P, Trichopoulos D, Ahrens W, Pigeot I, Merletti F, Richiardi L, Talamini R, Barzan L, Macfarlane GJ, Macfarlane TV, Holcátová I, Bencko V, Benhamou S, Bouchardy C, Kjaerheim K, Lowry R, Agudo A, Castellsagué X, Conway DI, McKinney PA, Znaor A, McCartan BE, Healy CM, Marron M, Brennan P. Genetic associations of 115 polymorphisms with cancers of the upper aerodigestive tract across 10 European countries: the ARCAGE project. Cancer Res. 2009 Apr 1;69(7):2956-65.

     

    21.   Khrunin A, Mihailov E, Nikopensius T, Krjutskov K, Limborska S, Metspalu A Analysis of allele and haplotype diversity across 25 genomic regions in three Eastern European populations. Hum Hered. 2009;68(1):35-44

     

    22.   Landi MT, Chatterjee N, Yu K, Goldin LR., Goldstein AM, Rotunno M, Mirabello L, Jacobs K, Wheeler W, Yeager M, Bergen AW, Li Q, Consonni D, Pesatori AC, Wacholder S, Thun M, Diver R, Oken M, Virtamo J, Albanes D, Wang Z, Burdette L, Doheny KF, Pugh EW, Laurie C, Brennan P, Hung R, Gaborieau V, McKay JD, Lathrop M, McLaughlin J, Wang Y, Tsao M-S, Spitz MR, Wang Y, Krokan H, Vatten L, Skorpen F, Arnesen E, Benhamou S, Bouchard C, Metsapalu A, Vooder T, Nelis M, Välk K, Field JK, Chen C, Goodman G, Sulem P, Thorleifsson G, Rafnar T, Eisen T, Sauter W, Rosenberger A, Bickeboller H, Risch A, Chang-Claude J, Wichmann HE, Stefansson K, Houlston R, Amos CI, Fraumeni Jr. JF, Savage SA., Bertazzi PA, Tucker MA, Chanock S and Caporaso NE. A Genome-wide Association Study of Lung Cancer Identifies a Region of Chromosome 5p15 Associated with Risk for Adenocarcinoma The American Journal of Human Genetics 85, 1–13, November 13, 2009

     

    23.   Lips EH, Gaborieau V, McKay JD, Chabrier A, Hung RJ, Boffetta P, Hashibe M, Zaridze D, Szeszenia-Dabrowska N, Lissowska J, Rudnai P, Fabianova E, Mates D, Bencko V, Foretova L, Janout V, Field JK, Liloglou T, Xinarianos G, McLaughlin J, Liu G, Skorpen F, Elvestad MB, Hveem K, Vatten L, Study E, Benhamou S, Lagiou P, Holcátová I, Merletti F, Kjaerheim K, Agudo A, Castellsagué X, Macfarlane TV, Barzan L, Canova C, Lowry R, Conway DI, Znaor A, Healy C, Curado MP, Koifman S, Eluf-Neto J, Matos E, Menezes A, Fernandez L, Metspalu A, Heath S, Lathrop M, Brennan P. Association between a 15q25 gene variant, smoking quantity and tobacco-related cancers among 17 000 individuals. Int J Epidemiol. 2009 Sep 23. [Epub ahead of print] PubMed PMID: 19776245.

     

    24.   Altmäe S, Haller K, Peters M, Saare M, Hovatta O, Stavreus-Evers A, Velthut A, Karro H, Metspalu A, Salumets A. Aromatase gene (CYP19A1) variants, female infertility and ovarian stimulation outcome: a preliminary report. Reprod Biomed Online. 2009 May;18(5):651-7. PubMed PMID: 19549443.

     

    25.   Saare M, Belousova A, Punab M, Peters M, Haller K, Ausmees K, Poolamets O, Karro H, Metspalu A, Salumets A. Androgen receptor gene haplotype is associated with male infertility. Int J Androl. 2008 Aug;31(4):395-402. PubMed PMID: 17651405.

     

    26.   Eduard Maron , Kristi Kallassalu , Anu Tammiste , Raivo Kolde, Jaak Vilo , Innar Tõru , Veiko Vasar, Jakov Shlik, Andres Metspalu, Peripheral gene expression profiling of CCK-4-induced panic in healthy subjects. Am J Med Genet B Neuropsychiatr Genet. Dec 2, 2008

     

    27.   Tamm R, Oselin K, Kallassalu K, Magi R, Anier K, Remm M, Metspalu A. Thiopurine S-methyltransferase (TPMT) pharmacogenetics: three new mutations and haplotype analysis in the Estonian population. Clin Chem Lab Med. 2008;46(7):974-9.

     

    28.   Janne Pullat, Wlad Kusnezow, Kaie Jaakson, Markus Beier, Jörg D. Hoheisel, Andres Metspalu, Arrayed primer extension on in situ synthesized 5´ → 3’ oligonucleotides in microchannels. New Biotechnology 2008 Aug 14.

     

    29.   Pullat, J.; Beier, M.; Hoheisel, J.; Metspalu, A. (2008). In situ Synthesised Oligonucleotide Microarray for Mutational Analysis and Genotyping of DNA. Genetics - Understanding Living Systems: XX International Congress of Genetics; Berlin, Germany; July 12-17, 2008.

     

    30.   Krjutskov K, Andreson R, Mägi R, Nikopensius T, Khrunin A, Mihailov E, Tammekivi V, Sork H, Remm M, Metspalu A. Development of a single tube 640-plex genotyping method for detection of nucleic acid variations on microarrays. Nucleic Acids Res. 2008 Jul;36(12):e75.

     

    31.   Pullat J, Metspalu A. Arrayed primer extension reaction for genotyping on oligonucleotide microarray. Methods Mol Biol. 2008;444:161-7.

     

    32.   Pullat J, Fleischer R, Becker N, Beier M, Metspalu A, Hoheisel JD. Optimization of candidate-gene SNP-genotyping by flexible oligonucleotide microarrays; analyzing variations in immune regulator genes of hay-fever samples. BMC Genomics. 2007 Aug 17;8:282.

     

    33.   Mägi R, Pfeufer A, Nelis M, Montpetit A, Metspalu A, Remm M. Evaluating the performance of commercial whole-genome marker sets for capturing common genetic variation. BMC Genomics. 2007 Jun 11;8:159.

     

     

    34.   Altmäe S, Haller K, Peters M, Hovatta O, Stavreus-Evers A, Karro H, Metspalu A, Salumets A. Allelic estrogen receptor 1 (ESR1) gene variants predict the outcome of ovarian stimulation in in vitro fertilization. Mol Hum Reprod. 2007 Aug;13(8):521-6. Epub 2007 May 30. PubMed PMID: 17540666.

     

    35.   Gardner P, Oitmaa E, Messner A, Hoefsloot L, Metspalu A, Schrijver I. Simultaneous multigene mutation detection in patients with sensorineural hearing loss through a novel diagnostic microarray: a new approach for newborn screening follow-up. Pediatrics. 2006 Sep;118(3):985-94. PubMed PMID: 16950989.

     

    36.   Shadrina M, Nikopensius T, Slominsky P, Illarioshkin S, Bagyeva G, Markova E, Ivanova-Smolenskaia I, Kurg A, Limborska S, Metspalu A. Association study of sporadic Parkinson's disease genetic risk factors in patients from Russia by APEX technology. Neurosci Lett. 2006 Sep 25;405(3):212-6. Epub 2006 Jul 28. PubMed PMID: 16876316.

     

    37.   Montpetit A, Nelis M, Laflamme P, Magi R, Ke X, Remm M, Cardon L, Hudson TJ, Metspalu A. An evaluation of the performance of tag SNPs derived from HapMap in a Caucasian population. PLoS Genet. 2006 Mar;2(3):e27. Epub 2006 Mar 10. PubMed PMID: 16532062; PubMed Central PMCID: PMC1391920.

     

    38.   Kõks S, Nikopensius T, Koido K, Maron E, Altmäe S, Heinaste E, Vabrit K,Tammekivi V, Hallast P, Kurg A, Shlik J, Vasar V, Metspalu A, Vasar E. Analysis of SNP profiles in patients with major depressive disorder. Int J Neuropsychopharmacol. 2006 Apr;9(2):167-74. Epub 2005 Jun 1. PubMed PMID: 15927089.

     

    39.   Schrijver I, Oitmaa E, Metspalu A, Gardner P. Genotyping microarray for the detection of more than 200 CFTR mutations in ethnically diverse populations. J Mol Diagn. 2005 Aug;7(3):375-87. PubMed PMID: 16049310; PubMed Central PMCID: PMC1867536.

     

    40.   Le Calvez F, Ahman A, Tonisson N, Lambert J, Temam S, Brennan P, Zaridze DG, Metspalu A, Hainaut P. Arrayed primer extension resequencing of mutations in the TP53 tumor suppressor gene: comparison with denaturing HPLC and direct sequencing. Clin Chem. 2005 Jul;51(7):1284-7. PubMed PMID: 15976115.

     

    41.   Maron E, Nikopensius T, Kõks S, Altmäe S, Heinaste E, Vabrit K, Tammekivi V, Hallast P, Koido K, Kurg A, Metspalu A, Vasar E, Vasar V, Shlik J. Association study of 90 candidate gene polymorphisms in panic disorder. Psychiatr Genet. 2005 Mar;15(1):17-24. PubMed PMID: 15722953.

     

    42.   Mueller JC, Lõhmussaar E, Mägi R, Remm M, Bettecken T, Lichtner P, Biskup S, Illig T, Pfeufer A, Luedemann J, Schreiber S, Pramstaller P, Pichler I, Romeo G, Gaddi A, Testa A, Wichmann HE, Metspalu A, Meitinger T. Linkage disequilibrium patterns and tagSNP transferability among European populations. Am J Hum Genet. 2005 Mar;76(3):387-98. Epub 2005 Jan 6. PubMed PMID: 15637659; PubMed Central PMCID: PMC1196391.

     

    43.   Metspalu A, Köhler F, Laschinski G, Ganten D, Roots I. [The Estonian Genome Project in the context of European genome research]. Dtsch Med Wochenschr. 2004 Apr 30;129 Suppl 1:S25-8. Review. German. PubMed PMID: 15133739.

     

    44.   Metspalu A. Estonian Genome Project--before the take-off and take-off. Bioinformatics. 2002;18 Suppl 2:S152. PubMed PMID: 12385997.

     

    45.   Metspalu, A. Estonian Genome Project. Drug Metabolism Reviews, 2002,34, 3-3.

     

    46.   Metspalu, A. Geenivaramu geneetikast. Eesti Arst, 6, 352-354.